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High-Sensitivity CRP (hs-CRP)

C-reactive protein is an acute-phase reactant synthesized by the liver in response to cytokines. High-sensitivity CRP (hs-CRP) measures low levels of chronic systemic inflammation, a primary driver of atherosclerosis and aging.

Optimal Targets

Cardiovascular Risk hs-CRP Level
Low (Optimal)< 1.0 mg/L
Average1.0 - 3.0 mg/L
High> 3.0 mg/L

Common Mistakes

  • Testing When Sick: hs-CRP spikes during acute infections or after intense exercise (like a marathon). Retest 2-3 weeks after illness.

Frequently Asked Questions

Q: How do I lower it?
A: Addressing visceral fat (which secretes inflammatory cytokines), treating sleep apnea, optimizing omega-3 index, and resolving chronic infections (including dental).

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