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Epigenetic Biological Age Clocks
Epigenetic clocks measure patterns of DNA methylation to estimate biological age, providing a proxy for how fast you are aging at a cellular level compared to your chronological age.
Types of Clocks
| Clock Generation | What it Measures |
|---|---|
| First Gen (Horvath) | Trained on chronological age. Good for forensics, bad for health optimization. |
| Second Gen (PhenoAge) | Trained on morbidity/mortality risk factors. |
| Third Gen (DunedinPACE) | Measures the *pace* of aging (e.g., aging 0.8 years per 1 chronological year). |
Common Mistakes
- Chasing the Number: The exact "age" output is less important than the rate of change between tests after an intervention.
Frequently Asked Questions
Q: Are at-home kits accurate?
A: Companies like TruDiagnostic (using DunedinPACE) provide highly validated lab results from simple blood spots.